Evidence map›Paper›PMID 40657269›Full record

ArticleIJTLD open2025

Early surgical intervention for extensive nontuberculous mycobacterial pulmonary disease.

T-F Kuo, M-R Lee, H-L Huang, K-C Chen, M-W Lin, S-W Kuo, P-M Huang, H-H Chen, J-Y Wang, J-S Chen

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PubMed Full text at PMC Publisher
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Successful management of fistulous empyema caused byRespiratory medicine case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T-F KuoDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
M-R LeeDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
H-L HuangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan (R.O.C).
K-C ChenDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
M-W LinDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
S-W KuoDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
P-M HuangDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
H-H ChenInstitute of Epidemiology and Preventive Medicine, National Taiwan University College of Public Health, Taipei, Taiwan (R.O.C).
J-Y WangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).
J-S ChenDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (R.O.C).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdjuvant lung resection surgery benefits selected patients with nontuberculous mycobacterial pulmonary disease (NTM-PD); however, optimal timing remains controversial. This study evaluated surgical outcomes and prognostic factors, with a focus on the timing of surgical intervention.

methodsThis study included 41 patients with NTM-PD who underwent adjuvant lung resection surgery between January 2000 and August 2022. Data on patient characteristics, surgical procedures and postoperative outcomes were analyzed. The primary outcome, defined as freedom from unfavorable outcomes (mortality, failure to achieve sputum culture conversion, or microbiological recurrence), was estimated using the Kaplan-Meier method, with prognostic factors analyzed by Cox regression model.

resultsExtensive disease was observed in 35 (85%) patients. The median preoperative antibiotic duration was 3.2 months. Twenty-two (54%) patients received lobectomies, whereas 15 (37%) received wedge resections. Thirty-four (83%) achieved sputum culture conversion. The probability of being free from unfavorable outcomes within two years was 80%. Independent favorable prognostic factors included body mass index ≥ 18.5 kg/m

conclusionsEarly surgical intervention, irrespective of the surgical approach, appeared feasible and potentially beneficial even in patients with extensive NTM-PD.

Indexed as

lobectomyNTM-PDpneumonectomypreoperative antibiotic durationsegmentectomywedge resection

Identifiers

PMID40657269
PMCPMC12248408

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