ArticleIJTLD open2025
Post-TB lung function, quality of life, and radiographic findings in children.
Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07097961 (Paediatric Post-TB Home-based Pulmonary Rehabilitation Feasibility Study), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Paediatric Post-TB Home-based Pulmonary Rehabilitation Feasibility Study
Who cites it
4 citing papers in PubMed.
- Post-Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management.MedComm · 2026Review
- Chronic Pulmonary Aspergillosis in Children: A Scoping Global Review.Open forum infectious diseases · 2026Article
- Lung function impairment in children post-tuberculosis treatment: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Review
- Hospitalization for tuberculosis in children and adolescents: clinical, epidemiological characteristics and post-treatment sequelae at a referral center in Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThe long-term effects of pulmonary TB (PTB) on pediatric lung health are poorly understood. Our objective was to assess predictors of lung function and describe health-related quality of life (QoL) and chest radiograph findings in children following PTB treatment in Kampala, Uganda.
methodsWe performed a cross-sectional study of children aged 6-16 years who completed PTB treatment within the last five years compared to household controls with no history of active TB. Children underwent chest radiograph, St. George's Respiratory Questionnaire, and spirometry. Mixed-effects regression models were performed to assess predictors of lung function impairment.
resultsWe enrolled 73 children with prior TB and 49 controls. In univariate mixed-effects regression models, prior TB was associated with lower FEV1 and FVC Z-scores (p<0.05). In multivariate models, BMI-for-age Z-score predicted FVC-Z-score (p<0.001). Fibrosis and pleural thickening were common radiographic abnormalities among children with prior TB. Median SGRQ total score was higher among children with prior TB (p<0.001).
conclusionChildren with prior TB showed reduced lung function and QoL compared to household controls. Our findings support the need for routine clinical follow-up after TB treatment.
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Registered trials
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