ArticleFrontiers in neuroimaging2025
Association of cervical artery stenosis with common cerebral microvascular lesions and coronary artery calcifications.
Article in Frontiers in neuroimaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: A connection between cerebral white matter hyperintensities and coronary artery disease is widely discussed. Both conditions are more prevalent in the elderly. While white matter hyperintensities are often associated with small vessel disease, atherosclerosis is the primary cause of coronary artery disease. Methods: We evaluated staging CT scans of the body and staging brain MRIs from patients with newly diagnosed malignant melanoma (without metastasis) between 01/01/2015 and 06/30/2023. CT scans were assessed for coronary artery disease using a modified overall visual assessment. Fazekas scores were used to evaluate the MRI for white matter changes. Additional clinical data were obtained from digital patient records. Results: We analyzed data from 120 patients (57 females, mean age 68 years, standard deviation 14 years) and found a correlation between coronary artery disease and both age ( Conclusion: There is a significant correlation between white matter hyperintensities and both carotid stenoses and coronary artery disease. This finding is clinically relevant: in patients with white matter hyperintensities and coronary artery disease, carotid stenosis should be ruled out.
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