ArticleSmall science2025
Bovine Serum Albumin-Based Sponges as Biocompatible Adsorbents: Development, Characterization, and Perfluorooctane Sulfonate Removal Efficiency.
Article in Small science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bovine Serum Albumin-Trypsin Sponges for Enhanced Enzymatic Stability and Protein Digestion Efficiency.ACS applied bio materials · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyfluoroalkyl substances, particularly perfluorooctane sulfonate (PFOS), are persistent environmental pollutants with severe health risks due to their bioaccumulation and resistance to degradation. Current PFOS removal technologies are limited by either efficiency, cost, or environmental concerns. Here, we introduce a biocompatible, protein-based sponge approach using bovine serum albumin (BSA) as a scaffold for efficient PFOS removal. We developed highly porous, mechanically robust sponges by optimizing foaming parameters such as mixing speed, duration, and surfactant concentration. Advanced characterization techniques, including microcomputed tomography and cryo-scanning electron microscopy, confirmed the sponges' structural integrity. Leveraging natural BSA-PFOS interactions, the sponges demonstrate effective PFOS removal, achieving up to ≈80% efficiency at a pH of ≈7.4, similar to natural water systems. Adsorption behavior is described using Langmuir and Freundlich isotherms, showing high adsorption capacity and surface interaction. Mechanical testing confirmed durability, making the sponges suitable for real-world applications. This eco-friendly method surpasses conventional PFOS removal techniques, offering a cost-effective solution with potential applications in drug delivery, tissue engineering, and catalysis. This work paves the way for developing multifunctional, porous protein-based materials that address urgent environmental challenges while offering versatile applications in biotechnology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.