Evidence map›Paper›PMID 40657048›Full record

ArticleIEEE open journal of engineering in medicine and biology2025

Biomimetic Chitosan-Based Hydrogels for Sustainable Wound Healing With AI/ML Insights.

Shourya Bodla, Prince Jain, Anwesha Khanra, Chhavi Sharma, Anupam Jyoti, Shiv Dutt Purohit, Hemant Singh, Abhijeet Singh, Juhi Saxena

Abstract read
In one paragraph

Article in IEEE open journal of engineering in medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shourya BodlaDepartment of Biotechnology, Parul Institute of TechnologyParul University Vadodara 391760 India.ORCID https://orcid.org/0009-0003-8393-3112
Prince JainDepartment of Mechatronics Engineering, Parul Institute of TechnologyParul University Vadodara 391760 India.ORCID https://orcid.org/0000-0002-7950-7263
Anwesha KhanraDepartment of Biotechnology, Parul Institute of TechnologyParul University Vadodara 391760 India.
Chhavi SharmaUniversity Centre for Research and Development, University Institute of BiotechnologyChandigarh University Mohali 140413 India.ORCID https://orcid.org/0000-0003-3118-5100
Anupam JyotiInflammation Research Laboratory, Department of Life Science, Parul Institute of Applied ScienceParul University Vadodara 391760 India.
Shiv Dutt PurohitDepartment of Biomedical Engineering and BiotechnologyKhalifa University Abu Dhabi 127788 United Arab Emirates.ORCID https://orcid.org/0000-0002-1423-521X
Hemant SinghDepartment of Biological SciencesKhalifa University of Science and Technology Abu Dhabi 127788 United Arab Emirates.
Abhijeet SinghCancer Research Laboratory, Department of BiosciencesManipal University Jaipur 303007 India.ORCID https://orcid.org/0000-0001-5274-6080
Juhi SaxenaDepartment of Biotechnology, Parul Institute of TechnologyParul University Vadodara 391760 India.ORCID https://orcid.org/0000-0002-4135-7466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing process is associated with multifaceted complications and is a functional way to advance the therapeutic process. Polymeric biomaterials exhibit structural mimicry with the extracellular matrix of the tissue to be regenerated and they also avoid chronic inflammation and immunological responses. Chitosan, a biopolymer demonstrates exceptional healing properties because of its biocompatibility, biodegradability, antimicrobial nature and affinity for biomolecules. Biomaterials consisting of chitosan along with herbal extracts could be ideal for wound healing. Click chemistry can provide one of the best ways to combine these bio-actives with chitosan. Advancing wound healing strategies with artificial intelligence /machine learning approaches can be employed further to boost the clinical efficacies of bioactive-loaded chitosan composite hydrogels. This review article investigates functionalized wound dressings with special emphasis on chitosan-based hydrogels, their effects on wound healing, and advanced approaches to increase hydrogel benefits by adding bioactive substances to form nanocomposites.

Indexed as

Artificial intelligencebiomimetic hydrogelsclick chemistrysustainable development goal 3wound healing

Identifiers

PMID40657048
PMCPMC12251101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.