Evidence map›Paper›PMID 40656986›Full record

ArticleBiology of sport2025

Genetic prediction of lower limb isometric strength changes after 12 weeks of resistance training.

Tao Mei, Yanchun Li, Dapeng Bao, Xiangang Yang, Xiaolin Yang, Liang Li, Zihong He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology of sport, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tao MeiChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Yanchun LiChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Dapeng BaoChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Xiangang YangHebei Sport University, Hebei, China.
Xiaolin YangChina Institute of Sport and Health Science, Beijing Sport University, Beijing, China.
Liang LiSultan Idris Education University, Tanjung Malin, Malaysia.
Zihong HeBiological Science Research Center, China Institute of Sport Science, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to identify genetic variations associated with changes in isometric strength following resistance training and develop a predictive model for understanding training effects, providing insights for tailored fitness guidance. A 12-week resistance training program, consisting of traditional squats and bench press exercises, was completed by 193 healthy Chinese adults, with isometric strength assessed before and after the intervention. DNA was extracted for whole-genome genotyping, followed by genomewide association analysis using PLINK 1.9. Lasso regression was used to screen variables, and predictive models for training effectiveness were established using logistic regression, Nomogram, and stepwise linear regression. Following the training, participants showed an increased isometric strength (Δ = 8.69%, p = 0.08, ES = 0.07), ranging from -55.78% to 133.47%. Nineteen lead SNPs were significantly associated with improvements in lower limb isometric strength (p < 1 × 10

Indexed as

Genome-wide association analysisIndividual differencesIsometric contractionPredictive modelResistance training

Identifiers

PMID40656986
PMCPMC12244378

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.