Evidence map›Paper›PMID 40656962›Full record

ArticlePeerJ2025

Chronic sleep deprivation is associated with delayed puberty onset in rats, activation of proinflammatory cytokines and gut dysbiosis.

Shirley Priscilla Gunawan, Shih-Yi Huang, Jhih-Wei Hsu, Chia-Yuan Lin, Nam Nhat Nguyen, Te-Hsuan Tung, Shu-Ling Liang, Gilbert Aaron Lee, Chien-Tien Su, Yang Ching Chen

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Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shirley Priscilla Gunawan *Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei, Taiwan.
Shih-Yi Huang *Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei, Taiwan.
Jhih-Wei HsuDepartment of Family Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chia-Yuan LinDepartment of Family Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Nam Nhat NguyenCollege of Medicine, Taipei Medical University, Taipei, Taiwan.
Te-Hsuan TungSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Shu-Ling LiangDepartment of Physiology and Pharmacology, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Gilbert Aaron LeeChild Development Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
Chien-Tien SuSchool of Public Health, Taipei Medical University, Taipei, Taiwan.
Yang Ching ChenGraduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic sleep deprivation (CSD) in adolescents has become a trend with adverse health outcomes. Previous studies have demonstrated that sleep deprivation causes inflammation, alters puberty onset, and changes the gut microbiome composition; however, the relationship between these is still unknown. Therefore, we hypothesized that CSD delays the onset of puberty

Indexed as

CytokinesDysbiosisGastrointestinal MicrobiomePuberty, DelayedSexual MaturationSleep DeprivationAnimalsFemaleInflammationMaleRatsRats, Sprague-DawleyCytokinesChronic sleep deprivationGut microbiomeProinflammatory cytokinesPuberty onsetRodent model

Identifiers

PMID40656962
PMCPMC12255245

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.