Evidence map›Paper›PMID 40656940›Full record

SynthesisPeerJ2025

Neuroprotective effects of essential oils in animal models of Alzheimer's and Parkinson's disease: a systematic review.

Adrielle do Espírito Santos Macedo, Thayná Moraes Ferreira, Lane Viana Krejcová, Fernando Allan de Farias Rocha, Joyce Kelly R da Silva, Laís Resque Russo Pedrosa, Bruno Duarte Gomes

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Integrative phytochemical profiling andFrontiers in nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrielle do Espírito Santos MacedoLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Thayná Moraes FerreiraLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Lane Viana KrejcováLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Fernando Allan de Farias RochaLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Joyce Kelly R da SilvaLaboratório de Bioprospecção de Inovação Tecnológica de Produtos Naturais da Amazônia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Laís Resque Russo PedrosaLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Bruno Duarte GomesLaboratório de Neurofisiologia Eduardo Oswaldo Cruz, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.ORCID 0000-0002-3646-7847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs), derived from aromatic plants, have garnered significant attention for their potential neuroprotective properties in neurodegenerative diseases. This systematic review evaluates recent advancements in understanding the neuroprotective role of EOs against Alzheimer's disease (AD) and Parkinson's disease (PD). Following PRISMA guidelines, we conducted a comprehensive literature search across three major databases (PubMed, Virtual Health Library, and Web of Science) from inception to January 2024, resulting in thirteen high-quality

Indexed as

Alzheimer DiseaseNeuroprotective AgentsOils, VolatileParkinson DiseaseAnimalsDisease Models, AnimalMiceOxidative StressRatsNeuroprotective AgentsOils, VolatileAlzheimer’s diseaseEssential oilsNeuroprotectionParkinson’s diseaseSystematic review

Identifiers

PMID40656940
PMCPMC12256039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.