ArticleFrontiers in physiology2025
Optimization of secondary flow path clearance in centrifugal blood pump: a combined numerical and experimental study.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Blood pumps as mechanical circulatory support (MCS) devices are widely used for patients with ventricular heart failure, and improving blood compatibility remains a key focus for researchers. Methods: The effects of secondary flow path clearance on the performance and hemocompatibility of a centrifugal blood pump are investigated in this study. A blood pump of the specific design was developed for modeling and computer simulation, and 25 models were generated by varying its internal and outer clearance between 600 and 1,000 μm. This study systematically investigates the hydrodynamic and hemodynamic performance of designed blood pumps through integrated computational fluid dynamics simulations and Results: Key findings reveal a strong agreement between numerical predictions and experimental data, showing a maximum pressure deviation of 9% for the baseline pump configuration. Furthermore, the effect of the change in clearance on the head and efficiency is less than ±3%. The change in the secondary flow path significantly impacts hemolysis performance. Discussion: An optimal clearance combination exists in the designed model, and for a specific flow field structure, asymmetric clearance may be an effective means to balance leakage control and turbulence suppression. Although the findings are specific to the pumps examined in this study, they provide valuable insights into the optimal design of blood pumps.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.