Evidence map›Paper›PMID 40656870›Full record

ArticleJournal of ultrasonography2025

Diagnostic cut-off values and grading of carpal tunnel syndrome by shear wave elastography at different tunnel locations correlated with gold standard nerve conduction study - a case-control study.

Prashat Bhalke, Priya Pattath Sankaran, Arvind N Prabhu, Rajagopal Kadavigere, Prakashini Koteshwara

Abstract read
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Article in Journal of ultrasonography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prashat BhalkeDepartment of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0009-0008-3814-5623
Priya Pattath SankaranDepartment of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0002-7201-5733
Arvind N PrabhuDepartment of Neurology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0002-1999-0206
Rajagopal KadavigereDepartment of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0003-3486-8740
Prakashini KoteshwaraDepartment of Radiodiagnosis, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0001-6385-5709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The gold standard nerve conduction study for diagnosing carpal tunnel syndrome is often painful and has variable diagnostic accuracy. This study aimed to evaluate the diagnostic performance of shear wave elastography in correlation with nerve conduction study. Material and methods: A prospective case-control study was conducted on 50 participants (50 wrists), including 25 carpal tunnel syndrome cases diagnosed by nerve conduction study and 25 healthy controls. Shear wave elastography assessed the stiffness of the median nerve at three locations: outside the carpal tunnel, at the inlet, and at the outlet. Cross-sectional area measurements were also obtained using B-mode ultrasound. Receiver operating characteristic curves were used to evaluate diagnostic performance. Results: Shear wave elastography and cross-sectional area demonstrated high diagnostic accuracy for carpal tunnel syndrome, with a cut-off value of ≥63.5 kPa inside the tunnel (mean of inlet and outlet values) and a cross-sectional area cut-off of ≥0.08 cm Conclusions: Shear wave elastography is a reliable, non-invasive modality for carpal tunnel syndrome diagnosis, offering excellent specificity, particularly when combined with cross-sectional area. Additionally, shear wave elastography at the tunnel inlet may help identify severe carpal tunnel syndrome, supporting timely clinical decision-making and prioritization of intervention.

Indexed as

carpal tunnel syndromemedian nervenerve conduction studyshear wave elastographyultrasound

Identifiers

PMID40656870
PMCPMC12255475

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