Evidence map›Paper›PMID 40656788›Full record

ArticleCardiovascular diagnosis and therapy2025

Comparative evaluation of 5.0 T and 3.0 T time-of-flight magnetic resonance angiography in assessing collateral circulation in moyamoya angiopathy.

Yijun Zhou, Yuanren Zhai, Shihai Zhao, Ke Xue, Yuxin Yang, Gan Sun, Zhengyu Xu, Mingli Li, Jun Ni, Dong Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yijun ZhouDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yuanren ZhaiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Shihai ZhaoDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ke XueMR Collaboration, United Imaging Research Institute of Intelligent Imaging, Beijing, China.
Yuxin YangMR Collaboration, United Imaging Research Institute of Intelligent Imaging, Beijing, China.
Gan SunTheranostics and Translational Research Center, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Zhengyu XuTheranostics and Translational Research Center, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Mingli LiDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jun NiDepartment of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Dong ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yining WangDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Feng FengDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Time-of-flight magnetic resonance angiography (TOF MRA) is a widely recognized noninvasive diagnostic tool of moyamoya angiopathy (MMA). 3.0 T TOF MRA may lack the precision needed to evaluate collaterals in MMA, whereas 5.0 T TOF MRA may enable better visualization of collateral vessels. This study compared the efficacy of 5.0 T and 3.0 T TOF MRA in assessing collateral circulation in patients with MMA. Methods: A total of 21 patients diagnosed with MMA [male 11; mean age: 35 years (range, 18-57 years)] was included in this study. Qualitative assessments encompassed imaging of the terminal internal carotid arteries (ICAs), distal middle cerebral arteries (MCAs), moyamoya vessels (MMVs), and leptomeningeal anastomosis (LMA) collaterals, using digital subtraction angiography (DSA) as a reference. A semi-quantitative grading system was employed with both 5.0 T and 3.0 T MRI to assess MMV visibility and LMA collaterals, using MMV area scores and leptomeningeal system scores. Results: The 5.0 T TOF MRA showed better scores for visualization of distal MCAs, MMVs, and LMA collaterals than 3.0 T TOF MRA (P<0.05 for both observers). The 5.0 T TOF MRA demonstrated superior detection capabilities. It showed higher MMV area scores, indicating better visibility of MMVs (z=4.41, P<0.001), and higher leptomeningeal system scores (z=3.72, P<0.001) compared to 3.0 T MRA. Conclusions: The 5.0 T TOF MRA demonstrates potential as an assessment tool for MMA, providing enhanced visualization of abnormal vascular networks.

Indexed as

5.0 Tmagnetic resonance angiography (MRA)moyamoya disease (MMD)vascular disorders

Identifiers

PMID40656788
PMCPMC12246984

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