Evidence map›Paper›PMID 40656765›Full record

ReviewDiscoveries (Craiova, Romania)

Heartbreakers: Decoding the Molecular Dynamics of Stimulants Abuse on the Cardiovascular System.

Cristina Mihaela Stirbu, Anisia-Cristiana Vasiliniuc, Anda Vasiliu, Elisa Anamaria Liehn

Abstract readReview
In one paragraph

Review in Discoveries (Craiova, Romania). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristina Mihaela StirbuCenter of Innovation and e-Health, Carol Davila University of Medicine and Pharmacy, Strada Dionisie Lupu 37, 030167 București, Bucharest, Romania.
Anisia-Cristiana VasiliniucCenter of Innovation and e-Health, Carol Davila University of Medicine and Pharmacy, Strada Dionisie Lupu 37, 030167 București, Bucharest, Romania.
Anda VasiliuCenter of Innovation and e-Health, Carol Davila University of Medicine and Pharmacy, Strada Dionisie Lupu 37, 030167 București, Bucharest, Romania.
Elisa Anamaria LiehnCenter of Innovation and e-Health, Carol Davila University of Medicine and Pharmacy, Strada Dionisie Lupu 37, 030167 București, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review explores the intricate relationship between stimulants abuse, particularly involving caffeine, amphetamines, methylphenidate and cocaine, offering a detailed and insightful overview of the multifaceted consequences of stimulant drug use on the cardiovascular system. Substance abuse is a medical and socioeconomic issue, which should be regarded properly with respect to its multifaceted implications. For instance, chronic usage exponentially increases the cardiovascular risk, leading to high morbidity and mortality rates. Arrhythmias, atherosclerosis, thrombosis and ischemia are just some of the direct effects of stimulants on vessels and heart, which lead in time to more severe pathological changes, such as hypertension, cardiomyopathies, valvulopathies, myocardial infarction, peripheral artery disease and other cerebrovascular diseases. The different approaches and diverse perspectives of this review, highlight the clinical significance of this complex field. Moreover, opportunities for further research and exploration are pointed out, thus  promoting public education, personalized medical approaches, and targeted interventions to mitigate the substantial morbidity and mortality linked to stimulant abuse. Hopefully, this effort will enhance public cardiovascular well-being.

Indexed as

Substance abuse; stimulants; cardiovascular disease; drug consumer

Identifiers

PMID40656765
PMCPMC12245559

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.