Evidence map›Paper›PMID 40656748›Full record

ArticleArthroscopy techniques2025

Arthroscopic Matrix-Associated Autologous Chondrocyte Implantation for Focal Tibial Defects.

Domenico Franco, Chilan B G Leite, Sebastian Schmidt, Nathan Sherman, Omar Protzuk, Christian Lattermann

Abstract read
In one paragraph

Article in Arthroscopy techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Domenico FrancoDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
Chilan B G LeiteDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
Sebastian SchmidtDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
Nathan ShermanDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
Omar ProtzukDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
Christian LattermannDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Damage to the articular cartilage of the tibial plateau presents significant challenges, resulting in pain, functional impairment, and progressive joint degeneration that can lead to severe osteoarthritis. Traditional open surgeries, although effective, are associated with substantial tissue disruption, prolonged recovery, and risks of complications. Here, we present an arthroscopic technique for matrix-associated autologous chondrocyte implantation tailored to address focal tibial cartilage defects. This technique integrates meticulous arthroscopic preparation of the defect site and precise implantation of the matrix-associated autologous chondrocyte implantation membrane. The postoperative protocol emphasizes gradual weight-bearing and progressive functional recovery, enabling a safe return to daily activities and sports.

Identifiers

PMID40656748
PMCPMC12255457

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.