Treatment of an Osteochondral Defect of the Trochlea Using Matrix-Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting.

Rishi Trikha, Thomas J Kremen, Paul J Walker, Kristofer J Jones

Abstract read

In one paragraph

Article in Arthroscopy techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rishi TrikhaDepartment of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.

Thomas J KremenDepartment of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.

Paul J WalkerDepartment of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.

Kristofer J JonesDepartment of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, U.S.A.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous chondrocyte implantation (MACI) for the appropriate patient has evolved as a reliable technique with encouraging long-term outcomes. Despite the reported favorable outcomes, there remains a relative dearth of literature on the use of MACI with autologous bone graft. This article presents a modified MACI sandwich technique that uses only 1 scaffold in combination with autologous bone graft from the proximal tibia to address an osteochondritis dissecans lesion of the lateral trochlea. This technique allows for both a stable MACI single-layer scaffold and a relatively efficient operative workflow.

Identifiers

PMID40656700

DOI10.1016/j.eats.2025.103507

PMCPMC12255428

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.