Evidence map›Paper›PMID 40656661›Full record

ArticleEquity neuroscience2025

Training Africans to Lead and Execute Neurological Trials and Studies (TALENTS): program overview and rationale.

Adewale E Ayodele, Iretioluwa M Bamtefa, IfeOluwa Owoseni, Erastus Amayo, Alfred Njamnshi, Adesola Ogunniyi, Paul Olowoyo, Rufus Akinyemi, Daniel Lackland, Mayowa Owolabi and 1 more

Abstract read
In one paragraph

Article in Equity neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adewale E AyodeleDepartment of Epidemiology and Medical Statistics, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.
Iretioluwa M BamtefaDepartment of Health Policy and Management, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.
IfeOluwa OwoseniDepartment of Epidemiology and Medical Statistics, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.
Erastus AmayoDepartment of Medical Microbiology and Immunology, University of Nairobi.
Alfred NjamnshiBrain Research Africa Initiative (BRAIN), Geneva, Switzerland and Yaoundé, Cameroon; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
Adesola OgunniyiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Paul OlowoyoDepartment of Medicine, Afe Babalola University, Ado-Ekiti, Nigeria.
Rufus AkinyemiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Daniel LacklandDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.
Mayowa OwolabiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Bruce OvbiageleDepartment of Neurology, University of California San Francisco, San Francisco, CA, United States.

Funding

H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
Growing Data-science Research in Africa to Stimulate Progress (GRASP)UE5HL172183 · NHLBI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI FATUMO, SEGUN, OVBIAGELE, BRUCE · 2023 to 2025
$568k
Sub-Saharan Africa Conference on Stroke (SSACS) ConferenceR13NS115395 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE · 2020 to 2020
$50k
FIC NIH HHS D43 TW012030NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NHLBI NIH HHS UE5 HL172183NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R13 NS115395
6 · The paper itself

Abstract

Africa bears a disproportionate burden of neurological diseases, yet clinical trials and research often lack representation from African populations, hindering the development of precision medicine for people of African ancestry. The Training Africans to Lead and Execute Neurological Trials and Studies (TALENTS) program, a Fogarty International Research Training D-43 initiative, aims to build sustainable neurological research capacity in Africa through a 5-year partnership between U.S. institutions, the University of Ibadan, and the African Academy of Neurology (AFAN). TALENTS recruits and trains 20 multidisciplinary African scholars post-doctoral researchers and clinicians in clinical neuroscience research, including trial design, multi-omics, and grant writing. Scholars complete an online Certificate in Clinical Research from the Medical University of South Carolina (MUSC), with four advancing to a Master's degree, preparing them as faculty for a new Master's in Neurological Research at the University of Ibadan. The program enhances mentorship and networking via AFAN meetings, peer mentoring, and monthly think tanks, fostering academic career development. Evaluation tracks scholars' academic positions, publications, and funding success. As of February 2025, 15 scholars across three cohorts have progressed, with notable career advancements, including faculty appointments and initiation of PhD study. TALENTS leverages Africa's diverse population and endemic neurological conditions to address global health disparities, aiming to produce a cadre of independent investigators contributing to neurological research and mentorship in Africa, with broader implications for African American health.

Indexed as

AfricaEducationNeurologyNeuroscienceResearchTrainingWorkforce

Identifiers

PMID40656661
PMCPMC12249344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.