Evidence map›Paper›PMID 40656618›Full record

ReviewAvicenna journal of phytomedicine

Effects of royal jelly consumption on inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials.

Shaghayegh Taheri, Hossein Bahari, Farshad Mirzavi, Pegah Rahbarinejad, Zohreh Sajadi Hezaveh, Armin Doostparast, Asghar Zarban, Elyas Nattagh-Eshtivani

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shaghayegh TaheriDepartment of Clinical Biochemistry, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Hossein BahariDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farshad MirzaviCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Pegah RahbarinejadDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Zohreh Sajadi HezavehFaculty of Medicine and Health, Department of Health Sciences, The University of Sydney, Sydney, NSW, Australia.
Armin DoostparastTransplant Research Center, Clinical Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Asghar ZarbanDepartment of Clinical Biochemistry, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Elyas Nattagh-EshtivaniDepartment of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This systematic review and meta-analysis examines the impact of royal jelly (RJ) on inflammation and oxidative stress. By synthesizing existing research, it aims to provide valuable insights into the potential health benefits of RJ. Materials and Methods: PubMed/Medline, Web of Science, and Scopus were searched until the end of December 2023. This meta-analysis included all randomized clinical trials assessing the effect of RJ supplements on serum levels of high-sensitivity C-reactive protein (hs-CRP), total antioxidant capacity (TAC), and malondialdehyde (MDA). A random-effects model was utilized to calculate the pooled mean differences (MD) and 95% confidence interval. Results: Seven suitable datasets from 6 trials were considered eligible. RJ supplementation significantly reduced MDA (WMD, -1.79 (-3.00 to -0.58), p=0.004; I Conclusion: Although this meta-analysis confirmed that RJ could be a useful intervention to reduce oxidative stress, this research should be updated in future due to the restricted number of trials.

Indexed as

AntioxidantC-reactive proteinMalondialdehydeMeta-analysisOxidation-reductionRoyal jelly

Identifiers

PMID40656618
PMCPMC12244952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.