Evidence map›Paper›PMID 40656508›Full record

ArticleSurgical neurology international2025

BurstDR™ spinal cord stimulation for chemotherapy-induced peripheral neuropathy.

Stephen Jaffee, Jyothika Mamagdi, Miriam Vaezi, Trent Kite, Bhavika Gupta, Samuel Valleta, Feno Monaco, Nestor Tomycz

Abstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephen JaffeeDepartment of Neurosurgery, Allegheny Health Network, Pittsburgh, United States.
Jyothika MamagdiDepartment of Hematology/Oncology, Allegheny Health Network, Pittsburgh, United States.
Miriam VaeziDepartment of Pain Medicine, Allegheny Health Network, Pittsburgh, United States.
Trent KiteDepartment of Neurosurgery, Allegheny Health Network, Pittsburgh, United States.
Bhavika GuptaDepartment of Neurosurgery, Allegheny Health Network, Pittsburgh, United States.
Samuel ValletaDepartment of Pain Medicine, Allegheny Health Network, Pittsburgh, United States.
Feno MonacoDepartment of Pain Medicine, Allegheny Health Network, Pittsburgh, United States.
Nestor TomyczDepartment of Neurosurgery, Allegheny Health Network, Pittsburgh, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common persistent adverse effects of chemotherapy affecting cancer survivors. Other than the use of duloxetine, no other intervention has a proven benefit for these patients. Here, a patient with multiple myeloma who developed CIPN experienced a significant reduction in their symptoms after the implantation of a spinal cord stimulator. Case Description: A 64-year-old male with a history of multiple myeloma presented with chronic pain 4 years after chemotherapy, followed by an autologous stem cell transplant. As the patient's symptoms were refractory to medical management, he underwent placement of a permanent spinal cord stimulator, resulting in 80% relief of calf pain and a 60% improvement in foot paresthesias/pain. Conclusion: Spinal cord stimulation proved effective in treating CIPN (CIPN following autologous stem cell transplant) in a 64-year-old male treated 4 years ago for multiple myeloma.

Indexed as

ChemotherapyNeuromodulationNeuropathyPain

Identifiers

PMID40656508
PMCPMC12255184

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.