Evidence map›Paper›PMID 40656497›Full record

ArticleSurgical neurology international2025

Glioma mimicking a cystic infectious disease: A case report of multifocal, multicentric cystic glioblastoma.

Daniel Kiss-Bodolay, Marc Weiner, Kristof Egervari, Gilles Eperon, Maria Isabel Vargas, Denis Migliorini, Johannes Lobrinus, Stephan Harbarth, Philippe Bijlenga

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel Kiss-BodolayDepartment of Neurosurgery, University Hospitals of Geneva, Geneva, Switzerland.
Marc WeinerDivision of Neurooncology, Department of Oncology, University Hospitals of Geneva, Geneva, Switzerland.
Kristof EgervariDivision of Neuropathology, Department of Clinical Pathology, University Hospitals of Geneva, Geneva, Switzerland.
Gilles EperonDivision of Tropical and Humanitarian Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Maria Isabel VargasDivision of Neuroradiology, Hirslanden Clinic, Chêne-Bougeries, Switzerland.
Denis MiglioriniDivision of Neurooncology, Department of Oncology, University Hospitals of Geneva, Geneva, Switzerland.
Johannes LobrinusDivision of Neuropathology, Department of Clinical Pathology, University Hospitals of Geneva, Geneva, Switzerland.
Stephan HarbarthDivision of Tropical and Humanitarian Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Philippe BijlengaDepartment of Neurosurgery, University Hospitals of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glioblastoma multiforme (GBM) is a highly aggressive malignant tumor known to be a great mimicker. Multicystic metastasis and cystic GBM are not rare but multicystic diffuse GBM was never reported before. Case Description: We describe here the clinical course, the radiological characteristics, and the management of a patient with a diffuse cystic brain lesion. Even though the comprehensive bacterial, fungal, and parasitic work-up came back negative twice, the radiological and biological findings of the case presented in this work mislead an experienced multidisciplinary team. In a somewhat unexpected way, the pathological results showed a high-grade glial tumor. Conclusion: The case reported herein is an important reminder of the highly multimorph characteristics of GBM and the challenging differential diagnosis of cystic brain lesions.

Indexed as

Cystic brain lesionCystic glioblastomaMulticentric glioblastomaMultifocal glioblastoma

Identifiers

PMID40656497
PMCPMC12255217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.