Evidence map›Paper›PMID 40656496›Full record

ReviewSurgical neurology international2025

Cerebrospinal fluid analysis in tuberculous meningitis: A literature review.

Akhmad Imron, Yulius Hermanto, Ahmad Rizal, Vycke Yunivita, Rovina Ruslami

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akhmad ImronDepartment of Neurosurgery, Padjadjaran University/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Yulius HermantoDepartment of Neurosurgery, Padjadjaran University/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Ahmad RizalDepartment of Neurology, Padjadjaran University/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Vycke YunivitaDepartment of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia.
Rovina RuslamiDepartment of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tuberculous meningitis (TBM) is the most common central nervous system infection of Methods: This scientific work aims to determine the penetration rate of first-line anti-TB drugs that are often used in patients infected with Results: The results of CSF analysis depend on the volume of CSF used, the delivery of the sample, and the technical expertise of the clinician. If clinically, a patient is suspected of having TBM even though the results of CSF analysis show negative results for Conclusion: The use of INH is beneficial because it has high bactericidal activity. Gatifloxacin and ciprofloxacin, which are included in the fluoroquinolone class of drugs, are safe to use even though their CSF penetration is not as good as levofloxacin.

Indexed as

Anti-tuberculosis drug penetrationCerebrospinal fluidTuberculous meningitis

Identifiers

PMID40656496
PMCPMC12255168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.