Evidence map›Paper›PMID 40656475›Full record

ReviewSurgical neurology international2025

Neuroimaging markers of intracranial hypertension in cerebral venous thrombosis: A systematic review and meta-analysis.

Abdulsalam M Aleid, Abdulmonem A Alhussain, Awn Abdulmohsen Alessa, Ibrahim Alahmed, Abdulmajeed Abdulaziz Aljabr, Hasan A AlAidarous, Loai Albinsaad, Abdulrahman Almoslem, Saud Nayef Aldanyowi, Sami F Almalki

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdulsalam M AleidDepartment of Surgery, Medical College, King Faisal University, Hofuf, Eastern Province, Saudi Arabia.
Abdulmonem A AlhussainDepartment of Neurosurgery, King Fahad Hospital, Hofuf, Eastern Province, Saudi Arabia.
Awn Abdulmohsen AlessaDepartment of Neurosurgery, King Fahad Hospital, Hofuf, Eastern Province, Saudi Arabia.
Ibrahim AlahmedDepartment of Neurosurgery, King Fahad Hospital, Hofuf, Eastern Province, Saudi Arabia.
Abdulmajeed Abdulaziz AljabrCollege of Medicine, King Saud bin Abdulaziz for Health Science, Riyadh, Saudi Arabia.
Hasan A AlAidarousDepartment of Surgery, Faculty of Medicine, Albaha University, Albaha, Saudi Arabia.
Loai AlbinsaadDepartment of Surgery, King Faisal University, Hofuf, Eastern Province, Saudi Arabia.
Abdulrahman AlmoslemDepartment of General Surgery, King Faisal University, Hofuf, Eastern Province, Saudi Arabia.
Saud Nayef AldanyowiDepartment of Surgery Orthopedic, King Faisal University, Hofuf, Eastern Province, Saudi Arabia.
Sami F AlmalkiDepartment of Surgery, Medical College, King Faisal University, Hofuf, Eastern Province, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cerebral venous thrombosis (CVT) is commonly associated with intracranial hypertension (IH), though its neuroimaging markers remain less well-defined. This study aims to systematically review and compare neuroimaging markers of IH in CVT and idiopathic IH (IIH) to better understand their diagnostic implications. Methods: A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. From inception to 2024, we searched PubMed, Web of Science, and Scopus for observational studies and randomized controlled trials focusing on neuroimaging findings in primary IH (i.e., IIH) and IH secondary to CVT. Data were extracted on neuroimaging outcomes, including peri-optic cerebrospinal fluid (CSF) pressure, optic nerve head protrusion, and others. Results: Six studies met the eligibility criteria, comprising three cohort studies and three case-control studies, with a combined total of 301 patients. The results indicated that peri-optic CSF pressure (Odds ratio [OR]: 5.85, Conclusion: Typical neuroimaging characteristics of IH (e.g., empty sella) are more frequently observed in idiopathic cases (i.e., IIH) than in secondary causes, such as IH resulting from CVT. These differences have the potential to enhance diagnostic precision and facilitate the development of improved imaging protocols.

Indexed as

Cerebral venous thrombosisIntracranial hypertensionMagnetic resonance imagingNeuroimagingSystematic review

Identifiers

PMID40656475
PMCPMC12255185

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.