Evidence map›Paper›PMID 40656450›Full record

ArticleCochrane evidence synthesis and methods2025

A New Process Model of Study Identification Specific to the Identification of Randomised Studies for Systematic Reviews of Medical Interventions.

Chris Cooper, Zahra Premji, Christine Worsley, Eve Tomlinson, Sarah Dawson, Emma Prentice

Erratum issuedAbstract read
In one paragraph

Article in Cochrane evidence synthesis and methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Chris CooperBristol Medical School (PHS) Bristol UK.ORCID 0000-0003-0864-5607
Zahra PremjiHealth Research Librarian University of Victoria Victoria Canada.ORCID 0000-0002-6899-0528
Christine WorsleyHead of Clinical Operations, Tolley Health Economics Buxton UK.
Eve TomlinsonBristol Medical School (PHS) Bristol UK.
Sarah DawsonBristol Medical School (PHS) Bristol UK.
Emma PrenticeTolley Health Economics Buxton UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent work has illustrated that the same process of study identification is used in systematic reviews irrespective of the studies or data needs required for synthesis. We question if different review types should have their own specific models of study identification, to ensure the appropriate and timely identification of studies/study reports and to minimise research waste. Objective: In this paper, we aim to:1. illustrate and report a new process model to identify randomised studies for systematic reviews of medical interventions; and2. situate the model in context of current practice using a worked example from a recent systematic review. Method: Our model splits the identification of studies from the identification of study reports by searching in distinct phases. It begins with searches of trials registry resources to identify studies, followed by searches of bibliographic databases to identify study reports or unregistered studies. Supplementary search methods are then used to identify unpublished studies. The model includes the possibility of secondary searches, and we consider the role of update searches. Conclusion: A case study illustrates the application of the method alongside operational guidance.

Identifiers

PMID40656450
PMCPMC12245088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.