ArticleCochrane evidence synthesis and methods2025
Should we adopt the case report format to report challenges in complicated evidence synthesis? A proposal and illustration of a case report of a complex search strategy for humanitarian interventions.
Article in Cochrane evidence synthesis and methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Should we adopt the case report format to report challenges in complicated evidence synthesis? A proposal and illustration of a case report of a complex search strategy for humanitarian interventions.Cochrane evidence synthesis and methods · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case reports represent a form of evidence in medicine which detail an unusual or novel clinical case in a short, published report, disseminated for the attention of clinical staff. This form of report is not common outside of clinical practice. We question if the adoption of the 'case report' might also be useful in evidence synthesis. This where the case represents a challenge in undertaking evidence synthesis and the report details not only the resolution but also shows the working to resolve the challenge. Our rationale is that methodological responses to problems arising in complicated evidence synthesis often go unreported. The risk is that lessons learned in developing evidence synthesis are lost if not recorded. This represents a form of research waste. We suggest that the adoption of the case report format might represent the opportunity to highlight not only a challenge (the case) but a worked example of a possible solution (the report). These case reports would represent a resting place for the case, with notes left behind for future researchers to follow. We provide an example of a case report: a complicated search strategy developed to inform an evidence gap map on the effects of interventions in humanitarian settings on food security outcomes in low and middle-income countries and specific high-income countries. Our report details the solution that we developed (the search strategy). We also illustrate how we conceptualised the search, and the approaches that we tested but rejected, and the ideas that we pursued.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.