Evidence map›Paper›PMID 40656413›Full record

ArticleCureus2025

Assessment of Acute Abdominal Pain in Children Presenting to the Emergency Department: A Retrospective Observational Study.

Faisal G Almalki, Najeeb Q Alqarni, Maram S Althagafi, Aljory S Al Eid, Ziyad A Badri, Mohammed I Alzahrani, Bsaim A Altirkistani, Asma H AbuGhasham, Malek A Alhnaidi

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Faisal G AlmalkiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Najeeb Q AlqarniDepartment of Pediatric Emergency Medicine, King Abdullah Specialized Children's Hospital, Ministry of National Guard Health Affairs, Western Region, Jeddah, SAU.
Maram S AlthagafiDepartment of Pediatric Emergency Medicine, King Abdullah Specialized Children's Hospital, Ministry of National Guard Health Affairs, Western Region, Jeddah, SAU.
Aljory S Al EidCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Ziyad A BadriCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Mohammed I AlzahraniCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Bsaim A AltirkistaniCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Asma H AbuGhashamCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Malek A AlhnaidiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to assess acute abdominal pain presentation in pediatric patients presenting to the emergency department.

methodsThis is a retrospective study in which data was collected from electronic medical records. Presentations, associated symptoms, findings on physical examination, documented diagnostic tests, and outcomes of patients were collected and examined. Two multivariate analysis models were used to investigate factors associated with acute medical abdomen and acute surgical abdomen.

resultsOut of 2,169 visits during the study period, 235 (10.8%) patients presented with acute abdominal pain. Forty-five (19%) patients had a surgical abdomen, while the remaining had an acute medical abdomen. The most prevalent diagnosis was "non-specific abdominal pain", constituting 61 (26%) patients. Both leukocytosis (OR: 0.15; 95% CI: 0.03-0.51; p = 0.006) and right lower quadrant pain (OR: 0.26; 95% CI: 0.08-0.81; p = 0.021) were inversely associated with an acute surgical abdomen and were more suggestive of an acute medical abdomen. In contrast, right lower quadrant pain (OR: 13.9; 95% CI: 5.03-43.5; p < 0.001), leukocytosis (OR: 3.26; 95% CI: 1.07-11.1; p = 0.045), and neutrophilia (OR: 1.04; 95% CI: 1.01-1.09; p = 0.031) were found to be significantly associated with acute appendicitis.

conclusionPediatric patients' presentations to the emergency department exhibit a diversity of presentations, and diagnostics may be less evident compared to adult patients. Right lower quadrant pain and leukocytosis may be more indicative of a non-surgical abdomen rather than a surgical abdomen among different diagnoses that require surgical intervention. However, right lower quadrant pain and leukocytosis are still strongly associated with acute appendicitis out of different surgical diagnoses. To combine both findings, our conclusion is that right lower quadrant pain and leukocytosis are more predictive of an acute medical abdomen, but only when appendicitis is less likely to be one of the differential diagnoses. These findings challenge conventional clinical paradigms, suggesting that right lower quadrant pain could be a stronger predictor of medical conditions, which typically do not require surgical intervention.

Indexed as

abdominal painacute abdomenacute appendicitispediatricssurgical abdomen

Identifiers

PMID40656413
PMCPMC12256096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.