ArticleCureus2025
Isolated Axillary Lymphadenopathy Presenting as Carcinoma of Unknown Primary in a Female Patient: A Diagnostic and Therapeutic Challenge.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carcinoma of unknown primary (CUP) is a distinct and uncommon clinical entity characterized by metastatic disease without an identifiable primary tumor, despite thorough investigation. Isolated axillary lymphadenopathy as the sole manifestation is rare and diagnostically challenging, particularly in younger women. The patient was a 47-year-old woman with painless right axillary swelling with no breast or systemic lesions. Fine-needle aspiration cytology (FNAC) suggested metastatic carcinoma. PET-CT showed a hypermetabolic right axillary mass without evidence of disease elsewhere. Excisional biopsy confirmed poorly differentiated carcinoma; immunohistochemistry (IHC) was positive for PanCK, CK7, TRPS1, and PAX8 with a high Ki-67 index (70%). A multidisciplinary decision led to axillary lymph node dissection, which revealed no residual metastatic disease. The follow-up PET-CT was normal. This case highlights the importance of a thorough diagnostic approach. IHC, advanced imaging, and multidisciplinary input are critical for diagnosis and management. CUP localized to lymph nodes may have a more favorable prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.