Evidence map›Paper›PMID 40656401›Full record

ArticleCureus2025

Endophthalmitis With Subretinal Abscesses Presenting as Charles Bonnet Syndrome in a Patient With Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia: A Case Report and Discussion of the Literature.

Leanna M Zelle, Jeffrey L Bodeen, Jonah Shah, Vaishnavi Balendiran, Ahmed Elkeeb

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leanna M ZelleOphthalmology, University of Missouri, Columbia, USA.
Jeffrey L BodeenOphthalmology, University of Missouri, Columbia, USA.
Jonah ShahOphthalmology, University of Missouri, Columbia, USA.
Vaishnavi BalendiranOphthalmology, University of Missouri, Columbia, USA.
Ahmed ElkeebOphthalmology, University of Missouri, Columbia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 73-year-old male with recurrent necrotizing fasciitis and methicillin-resistant Staphylococcus aureus (MRSA) bacteremia who developed visual hallucinations and altered mental status on post operative day one after undergoing right knee prosthetic joint infection washout. His visual acuity, which was self reported as previously "very good" decreased to hand motion in the right eye (OD) and 20/400-1 in the left eye (OS), and he described new visual hallucinations. Differentials included post operative delirium, stroke, and ocular infiltration of his bacteremia. He was evaluated by infectious disease, orthopedic surgery, neurology, and ophthalmology specialties, and was found to have bilateral endophthalmitis, Charles Bonnet syndrome, and bilateral subretinal abscesses. The patient was treated with intravenous (IV) antibiotics and surgical removal of his infected knee hardware; however, he and his family members ultimately made the decision to withdraw goal-directed care. We present this case to emphasize the importance of ophthalmologic evaluation and early intervention in patients with MRSA bacteremia and alterations in vision or mentation.

Indexed as

bacterial endogenous endophthalmitischarles bonnet syndromeintraocular antibioticsmrsa bacteremiapost-operative deliriumseptic arthritis of kneeserous retinal detachmentsubretinal abscess

Identifiers

PMID40656401
PMCPMC12246502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.