ArticleCureus2025
Impact of Body Adiposity (Lean and Fat Mass Distribution) on Bone Mineral Density in Postmenopausal Indian Women: A Cross-Sectional Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Osteoporosis and obesity are prevalent health conditions that share overlapping risk factors and physiological consequences. After menopause, hormonal changes impact both bone strength and fat distribution. Although fat mass (FM) and lean mass (LM) are important components of body composition, their separate effects on bone mineral density (BMD) are not well understood, especially among Indians. Objective The main objective of this study is to assess how body adiposity, such as FM and LM, is related to BMD in postmenopausal Indian women. Methods A total of 36 postmenopausal women participated in a cross-sectional study at a tertiary care hospital. Participants underwent dual-energy X-ray absorptiometry (DEXA) scans (Hologic Inc., Marlborough, MA, USA) to measure BMD at the spine, hip, wrist, and whole body, along with body composition assessments. Women with secondary causes of osteoporosis, or those on medications affecting bone metabolism, were excluded. Correlations between FM, LM, and BMD were assessed using statistical analysis. Results Among the participants (n = 36), 17 (47.2%) had osteopenia, nine (25.0%) had osteoporosis, and 10 (27.8%) had normal BMD. FM showed significant positive correlations with hip BMD (r = 0.457, p = 0.005), lumbar spine BMD (r = 0.373, p = 0.025), total body BMD (r = 0.349, p = 0.037), and whole-body bone mineral content (WB-BMC) (r = 0.498, p = 0.002). After statistical adjustment, LM correlations were weaker and not statistically significant. Conclusion In Indian postmenopausal women, FM is a stronger predictor of BMD than LM. These findings underscore the importance of considering body fat when assessing and managing osteoporosis risk in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.