Evidence map›Paper›PMID 40656336›Full record

ArticleCureus2025

Atypical Optic Neuritis as a Manifestation of Ocular Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Case Report.

Carlos Sequeira Quesada, Maria Alexandra Vega Monge

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carlos Sequeira QuesadaNeurology, Universidad de Costa Rica, San José, CRI.
Maria Alexandra Vega MongeInternal Medicine, Caja Costarricense del Seguro Social (CCSS), San José, CRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classic definitions describe optic neuritis as an acute, unilateral loss of vision accompanied by an afferent pupillary defect and eye pain, with normal ophthalmoscopy in most cases. Advancements in paraclinical tests have dichotomized clinical presentations into typical and atypical optic neuritis, with the latter requiring additional testing to establish a diagnosis of definite or probable optic neuritis. Compromise of the second cranial nerve in optic neuritis expands beyond inflammation and demyelination and includes systemic and infectious entities, more commonly catalyzing atypical clinical presentations. We present the case of a male patient with atypical optic neuritis, based on its clinical course and imaging findings, who was ultimately diagnosed with extranodal marginal zone B-cell lymphoma (EMZL), a type of non-Hodgkin MALT lymphoma. The effect of the optic nerve in this pathology has only been sparsely reported.

Indexed as

blindnesslymphomamaltneuritisoptic

Identifiers

PMID40656336
PMCPMC12255367

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.