Evidence map›Paper›PMID 40656314›Full record

ArticleCureus2025

Single-Pass Albumin Dialysis (SPAD) as a Therapeutic Extracorporeal Liver Support in a Low-Resource Setting: Case Report and Literature Review.

David Roman Hernández, Alicia Valdez-Gaona, Luis Arturo García-Velasco, Jordana S Lemus, Omar González Herrera, Guillermo Cardenas Membrila

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David Roman HernándezIntensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.
Alicia Valdez-GaonaIntensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.
Luis Arturo García-VelascoIntensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.
Jordana S LemusIntensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.
Omar González HerreraIntensive Care Unit, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Guillermo Cardenas MembrilaIntensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute liver failure, a condition marked by high mortality, leads to a loss of liver function that impairs the detoxification of substances such as bilirubin, ammonia, and lactate, as well as the liver's synthetic functions, causing damage to other organs. New extracorporeal therapies, including single-pass albumin dialysis (SPAD), have been developed to support liver function. We present a case of a 25-year-old male with no significant past medical history who presented with multiple organ failure and acute kidney injury that required continuous renal replacement therapy (CRRT) with continuous venovenous hemodiafiltration (CVVHDF), necessitating SPAD for the treatment of the liver failure.

Indexed as

acute kidney injury (aki)acute liver failure (alf)acute-on-chronic liver failure (aclf)continuous venovenous hemodiafiltration (cvvhdf)intermittent hemodialysis (ihd)molecular adsorbent recirculating system (mars)single-pass albumin dialysis (spad)

Identifiers

PMID40656314
PMCPMC12249485

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.