ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2025
Impact of cardiovascular comorbidities on echocardiographic parameters in aortic stenosis.
Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Comorbidities in aortic stenosis (AS) significantly impact treatment outcomes by influencing intervention timing, choice, and prognosis. Diseases affecting cardiac hemodynamics independently of AS progression may distort echocardiographic interpretation, risking misclassification of AS severity. Understanding how comorbidities alter key echocardiographic parameters may facilitate more precise evaluation. Aim: To assess the impact of common cardiovascular comorbidities on echocardiographic evaluation of AS. Material and methods: Medical records of 234 hospitalized patients with moderate/severe AS were retrospectively analyzed. Exclusion criteria included acute myocardial infarction, prior valvular surgery, and congenital heart defects. All patients underwent standard echocardiographic assessment during hospitalization. Results: Among the 234 patients (median age 76, 47.4% female), 85.0% had severe AS. The most prevalent comorbidities were hypertension (82.5%), chronic kidney disease (CKD, 45.3%), and type 2 diabetes (T2DM, 39.7%). Atrial fibrillation (AF) occurred in 33.8%, predominantly paroxysmal (49.4%). AF was associated with lower aortic valve mean pressure gradient (AVGmean, Conclusions: Comorbidities significantly affect echocardiographic parameters in AS, potentially leading to miscategorization of severity. The observed differences highlight a need for more comprehensive evaluation in multimorbid patients.
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