Evidence map›Paper›PMID 40656144›Full record

ArticleThe Pan African medical journal2025

Epidemiological and molecular profile of breast cancer: a retrospective study in Casablanca, Morocco.

Khadija Khadiri, Zineb Khadrouf, Abderrahmane Mellouki, Oumaima Bouchra, Amina Essalihi, Abdallah Naya, Majda Taoudi Benchekroun, Mehdi Karkouri

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Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khadija KhadiriLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Zineb KhadroufLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Abderrahmane MelloukiDepartment of Pathology, University Hospital Center Ibn Rochd, Casablanca, Morocco.
Oumaima BouchraLaboratory of Cellular and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.
Amina EssalihiLaboratory of Cellular and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.
Abdallah NayaLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Majda Taoudi BenchekrounLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco.
Mehdi KarkouriDepartment of Pathology, University Hospital Center Ibn Rochd, Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: breast cancer is a major public health concern in Morocco due to delayed diagnosis and treatment, largely due to its high incidence. It is the most prevalent cancer in women. This study aimed to report the epidemiological and the molecular profile of invasive breast carcinoma using surrogate immunohistochemical markers. Methods: during 24 months from 1 Results: this epidemiological study reveals that the mean age of patients was 52 ± 12.27 years. The most common histological type is invasive breast carcinoma of no special type, which accounts for 90.5% (n=1,410) of cases. Regarding Ellis and Elston modified Scarff-Bloom-Richardson (SBR) grade, grade III was the most common, 52.2% (n=521), followed by grade II, 44% (n=438), and grade I, 3.8% (n=38), as assessed by the SBR grade. The molecular classification results indicate that luminal B was the most common subtype at 52.2% (n=441), followed by triple-negative at 19.6% (n=166), with HER2 phenotype representing 17.4% (n=147) and luminal A at 10.8% (n=91). Conclusion: this study highlights that invasive breast carcinoma of no special type is the most common type, with grade III tumors being the most frequent. The majority of cases were luminal B, underscoring the need for targeted therapeutic strategies.

Indexed as

Breast NeoplasmsBreast Neoplasms, MaleAdultAgedAged, 80 and overBiomarkers, TumorFemaleHumansImmunohistochemistryMaleMiddle AgedMoroccoNeoplasm GradingRetrospective StudiesYoung AdultBiomarkers, TumorBreast cancerepidemiologyinvasive carcinomamolecular profileMorocco

Identifiers

PMID40656144
PMCPMC12245639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.