ReviewNeuroscience applied2024
Insomnia, anxiety and related disorders: a systematic review on clinical and therapeutic perspective with potential mechanisms underlying their complex link.
Review in Neuroscience applied, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review on Insomnia and Circadian Rhythms Desynchronization in Obsessive-Compulsive Disorder: From Childhood to Adulthood.Journal of sleep research · 2026Pooled it
- Lactiplantibacillus plantarum Lp815 improves sleep and increases urinary GABA in a randomized, double-blind, placebo-controlled study of sleep disturbance.Scientific reports · 2026Trial
- The Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TSC) in Community Mental Health: Evaluating Self-Reported Psychiatric Disorders as a Predictor of Symptoms and Treatment Outcome.Community mental health journal · 2026Article
- Sleep-Related Attentional Bias in Insomnia: A Drift Diffusion Model Approach.Journal of sleep research · 2026Article
- Sleep Characteristics and Insomnia Severity in Relation to Mediterranean Lifestyle Adherence and Psychosocial Wellbeing: Findings from the MEDIET4ALL International Survey.European journal of investigation in health, psychology and education · 2026Article
- Vital Exhaustion in Hospitalized Patients with Cardiovascular Disease: Associations with Anxiety and Insomnia-A Cross-Sectional Study.Journal of cardiovascular development and disease · 2026Article
- The complex relationship between endocrine and psychiatric disorders: an epidemiological study of risk estimates.Medicine and pharmacy reports · 2026Article
- Insomnia Severity in Psychiatric Outpatients: Real-World Insomnia Severity Index Data from an Italian Community Mental Health Center.Brain sciences · 2026Article
- Identification of distinct clinical phenotypes and their neurobiological signatures in stress-exposed individuals: A multimodal machine learning approach.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- The troy sleep scale: clinical validation and establishment of a screening cut-off.BMC psychology · 2026Article
- Network analysis of depression, anxiety, and NSSI symptoms in adolescents: a clinical sample study.BMC psychiatry · 2026Article
- Sex-specific associations of anxiety, insomnia, and their comorbidity with incident obesity in a general-population cohort.European journal of public health · 2026Article
- The multidimensional effects of sleep quality in young adults: the relationship between auditory performance, sound tolerance, and anxiety.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Insomnia contributes to paranoid thoughts through mechanisms involving anxiety and non-constructive rumination.Scientific reports · 2026Article
- Polygenic Index for Sleep Duration and Brain Changes over Time.Medical sciences (Basel, Switzerland) · 2026Article
- Stress ensemble in the BNST mediates comorbid anxiety and sleep disruption.Science advances · 2026Article
- Improved sleep quality is independently associated with decision-making recovery in panic disorder: a longitudinal study.Scientific reports · 2026Article
- Age of Onset in Insomnia: A Latent Profile Analysis.Journal of sleep research · 2026Article
- Heatwave-related variations in psychiatric consultations and admissions: a time-series analysis.Frontiers in psychiatry · 2026Article
- Sleep Disturbance in Adults with Type 2 Diabetes: Psychosocial Factors Across Anxiety Symptom Groups.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety and anxiety-related disorders are the most common mental disturbances, with dysregulation in emotions and cognition as central features. Since the function of sleep in regulating emotions, cognition stress response and inflammation is quintessential, sleep disturbances may be ideal modifiable factors in anxiety and related disorders. Accordingly, the aim of the review was to systematically review the association between insomnia symptoms and anxiety and related disorders. A systematic search has been conducted, and 93 papers have been selected for insomnia and General Anxiety Disorder, Panic Disorders, Social Anxiety Disorder, Separation anxiety, Obsessive Compulsive Disorder and Post Traumatic Stress Disorder, according to PRISMA. This review represents a comprehensive overview of clinical and therapeutic approaches to insomnia in the framework of anxiety and related disorders with a discussion of potential mechanisms underlying their complex link.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.