Evidence map›Paper›PMID 40656079›Full record

ReviewNeuroscience applied2024

Colour vision impairments in bipolar disorder: A systematic review.

Jason Tran, Arnav Gupta, Nicholas Fabiano, Vinita Dhir, Katherine Larose, Iris Lasker, Stanley Wong, Ibrahim Y Z Mohammad, Steven Le, Jess G Fiedorowicz and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neuroscience applied, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jason TranDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Arnav GuptaDepartment of Medicine, University of Calgary, Calgary, AB, Canada.
Nicholas FabianoDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.
Vinita DhirFaculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Katherine LaroseFaculty of Science, Carleton University, Ottawa, ON, Canada.
Iris LaskerFaculty of Social Science, University of Ottawa, Ottawa, ON, Canada.
Stanley WongDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Ibrahim Y Z MohammadDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Steven LeFaculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Jess G FiedorowiczDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.
Risa ShorrLearning Services, The Ottawa Hospital, Ottawa, ON, Canada.
Andrea ZampieriOphthalmology Unit Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy.
Alessio BellatoSchool of Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Samuele CorteseSchool of Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Marco SolmiDepartment of Psychiatry, University of Ottawa, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visual impairments are common in patients with bipolar disorder (BD), and the neuropathophysiology may suggest a potential influence on colour vision. This systematic review aimed to assess existing data of colour vision impairment, including chromatic discrimination and colour blindness in patients with BD. Comprehensive literature search compliant with PRISMA 2020 was conducted in Medline, Embase, and Google Scholar from inception to February 28th, 2023. Our inclusion criteria were: (1) patients with a diagnosis of bipolar I or II disorder based on DSM, ICD, or clinical diagnosis, and (2) study investigating colour vision (i.e., including colour blindness and discrimination), with (3) no restrictions on the condition of the comparator group. Study quality appraisal was performed using the NIH Study Quality Assessment Tool. Five studies from Brazil, Netherlands, and USA, with 338 patients were included. Three cross-sectional studies assessed chromatic discrimination and two case-series assessed colour blindness in patients with BD. The three cross-sectional studies support reduced chromatic discrimination during mild to moderate mania in BD when compared to healthy comparators. The latter two articles presented low evidence of an X-linked inheritance of BD. Our review indicates evidence of reduced chromatic discrimination in mild to moderate mania. However, further research is needed to validate these findings and to extend to other mood states in BD given current limitations. Future studies can benefit from further multi-institutional data, larger sample sizes, appropriate blinding, the use of biomarkers, and statistical adjustment to confounders to fully elucidate the role of chromatic discrimination in BD.

Indexed as

Bipolar disorderChromatic discriminationColor blindnessColour visionManiaVision changes

Identifiers

PMID40656079
PMCPMC12244176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.