ArticleJournal of pharmacy & bioallied sciences2025
Histo-Morphological Comparison of Placental Adaptations in Normal and Gestational Diabetes Mellitus Pregnancies and Their Impact on Neonatal Outcomes.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Assessment of the impact of oxidative stress and inflammation on placental angiogenesis in women with gestational diabetes mellitus (GDM).Reviews in endocrine & metabolic disorders · 2026Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gestational diabetes mellitus (GDM) significantly affects maternal and fetal health by altering placental structure and function, critical for fetal growth. Understanding the histomorphological changes in GDM-affected placentas can offer insight into how these adaptations impact pregnancy outcomes. Materials and Methods: This cross-sectional study examined 220 placental samples (110 from normal pregnancies and 110 from GDM-complicated pregnancies) collected from Index Medical College and Hospital. Morphological characteristics (shape, cotyledon count, cord insertion type), morphometric measurements (diameter, thickness, circumference, weight), and histological markers (syncytial knots, fibrinoid necrosis, villous fibrosis, and perivillous fibrin deposition) were assessed. Neonatal outcomes, including birth weight, APGAR scores, and fetoplacental weight ratio, were recorded and statistically analyzed. Results: Placentas from GDM pregnancies showed significantly higher weight (556.1 g vs. 498.8 g, Conclusion: The observed histomorphological changes in GDM placentas suggest compensatory mechanisms in response to the hyperglycemic environment but may also contribute to neonatal complications.
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