Evidence map›Paper›PMID 40655700›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Padmaksha Laskar, Kodithyala Hareesh Kumar, Tushar Kakkar, Mrunal Dave, Ruchi Patel, Naina Pattnaik, Mahesh Ghadage, Dipooja Patil

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Padmaksha LaskarDepartment of Maxillofacial Prosthodontics and Crown and Bridge and Oral Implantology, Sri Sai College of Dental Surgery, Kotherapally, Vikarabad, Hyderabad, Telangana, India.
Kodithyala Hareesh KumarDepartment of Periodontology, Meghana Institute of Dental Sciences, Warni Road, Mallaram, Nizamabad, Telangana, India.
Tushar KakkarAspen Dental, Pittsfield, Massachusetts, USA.
Mrunal DaveDDS, General Dentist, Private Practice, Pennsylvania, USA.
Ruchi PatelDepartment of Prosthodontics, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India.
Naina PattnaikDepartment of Periodontics and Oral Implantology, Kalinga Institute of Dental Science, KIIT Deemed to be University, Patia, Bhubaneswar, Odisha, India.
Mahesh GhadageDepartment of Prosthodontics and Crown and Bridge, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Dipooja PatilDepartment of Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Implant abutment materials significantly influence peri-implant tissue health, particularly the attachment and behavior of gingival fibroblasts. An optimal material can enhance biocompatibility and reduce inflammation, ensuring long-term success. This study compares the effects of titanium, zirconia, and polyetheretherketone (PEEK) abutments on gingival fibroblast attachment Materials and Methods: Standardized disks of titanium, zirconia, and PEEK abutment materials were prepared. Primary gingival fibroblasts were cultured and seeded on the disks in a 24-well plate format, with each material in triplicate. Cell attachment was assessed after 24 and 48 hours using fluorescence microscopy and a quantitative cell adhesion assay. Surface roughness (Ra) and hydrophilicity of the disks were evaluated to correlate with fibroblast behavior. Arbitrary values for attached cell counts and surface characteristics were analyzed using ANOVA and Results: Titanium demonstrated the highest fibroblast attachment (mean cell count: 1.25 × 10 Conclusion: Titanium and zirconia provide favorable conditions for gingival fibroblast attachment, with titanium slightly outperforming zirconia due to superior surface properties. PEEK, while biocompatible, demonstrates reduced fibroblast attachment, suggesting limited suitability for areas requiring strong soft tissue integration. These findings underscore the importance of material selection in achieving optimal peri-implant tissue health.

Indexed as

Gingival fibroblast attachmentimplant abutment materialstitanium

Identifiers

PMID40655700
PMCPMC12244781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.