Evidence map›Paper›PMID 40655629›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Evaluating Efficiency of Propofol and Dexmedetomidine for Hypotensive Anesthesia in ENT Operations.

P Kamesh Chandra, Dinesh Kumar Patel, Ranjeet Kumar Mohanty, Mohit Kulmi, Ramanpal Singh Makkad

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P Kamesh ChandraDepartment of Anaesthesiology and Critical Care, KIMS Seethammadhara, Visakhapatnam, Andhra Pradesh, India.
Dinesh Kumar PatelDepartment of Otorhinolaryngology, Late Shree Lakhiram Agarwal Memorial Government Medical College, Raigarh, Chhattisgarh, India.
Ranjeet Kumar MohantyDepartment of Anaesthesiology, District Headquarter Hospital, Sundargarh, Odisha, India.
Mohit KulmiDepartment of Pharmacology, DR. Laxmi Narayan Pandey Government Medical College, Ratlam, Madhya Pradesh, India.
Ramanpal Singh MakkadDepartment of Oral Medicine and Radiology, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: During ENT procedures, hypotensive anesthesia is essential for enhancing operative vision and reducing blood loss. Both dexmedetomidine and propofol are commonly used medications with different modes of action. The effectiveness of these medicines in producing controlled hypotension during ENT operations is assessed in this research. Materials and Methods: Sixty individuals between the ages of 18 and 60 who were having elective ENT operations participated in a prospective randomized clinical study. Patients were split into two groups: 30 patients in Group A got an infusion of propofol, and 30 patients in Group B received an infusion of dexmedetomidine. During surgery, hemodynamic measures such as heart rate (HR) and mean arterial pressure (MAP) were monitored. A visual analog scale (VAS) with a range of 0 (poor) to 10 (excellent) was used to evaluate the quality of the surgical field. Recovery periods were compared, and blood loss was noted. A paired Results: The mean MAP for Group B was 60 ± 4 mmHg ( Conclusion: During ENT procedures, dexmedetomidine was superior to propofol in terms of lowering intraoperative blood loss, enhancing surgical field quality, and producing controlled hypotension. Its usage, nevertheless, could be linked to somewhat longer recovery periods. In ENT procedures, dexmedetomidine is regarded as an excellent drug for hypotensive anesthesia.

Indexed as

Blood lossdexmedetomidineENT surgerieshypotensive anesthesiapropofolsurgical field quality

Identifiers

PMID40655629
PMCPMC12244641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.