Evidence map›Paper›PMID 40655620›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Enhanced Cleaning, Enhanced Healing: A Systematic Review of Advances in Endodontic Irrigation.

Shubhi Gupta, Karunakaran Venkataraman Jeyaraman, M Deepthi, Rohan Shinkre, Neha Singh, Sagar Shah

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shubhi GuptaDepartment of Conservative Dentistry and Endodontics, Private Practioner, Bareilly, Uttar Pradesh, India.
Karunakaran Venkataraman JeyaramanDepartment of Conservative Dentistry and Endodontics, JKK Nataraja Dental College and Hospital, Komarapalayam, Tamil Nadu, India.
M DeepthiDepartment of Conservative Dentistry and Endodontics, Dayananda Sagar College of Dental Science, Bengaluru, Karnataka, India.
Rohan ShinkreDepartment of Central Research Wing, K.L.E Society's Institute of Dental Sciences, Bengaluru, Karnataka, India.
Neha SinghDepartment of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, IMS, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Sagar ShahPrivate Practice (Shah Dental Clinic), Sangli, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Effective irrigation is crucial for successful endodontic treatment, ensuring debris removal, disinfection, and biofilm elimination. This systematic review analyzes recent advances in endodontic irrigants and activation systems. Materials and Methods: A comprehensive search of PubMed, Scopus, Web of Science, and Google Scholar was conducted to identify relevant studies published between 2015 and 2025. Results: Emerging irrigants, including nanoparticle-based solutions, herbal formulations, and photoactivated disinfectants, demonstrate promising antimicrobial and biocompatibility properties. Advanced irrigation activation techniques, such as ultrasonic, laser-activated, and multisonic irrigation, enhance root canal debridement efficacy. Conclusions: This review highlights the strengths and limitations of recent advancements in endodontic irrigation, providing insights into their clinical implications and future research directions.

Indexed as

Irrigationlaser activationnanoparticle

Identifiers

PMID40655620
PMCPMC12244762

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.