ArticleJournal of pharmacy & bioallied sciences2025
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oral mucosal healing is a complex biological process involving epithelial and connective tissue regeneration. The use of antioxidants has been proposed to accelerate healing by reducing oxidative stress and enhancing tissue repair. This study aimed to evaluate the effect of different antioxidants on oral mucosal healing in an Materials and Methods: Oral mucosal cells were cultured in a standard medium and subjected to scratch wound assays. The experimental groups included treatment with Vitamin C (100 μM), Vitamin E (50 μM), and a combination of both. A control group without antioxidant treatment was maintained. Healing was assessed at 24, 48, and 72 hours using image analysis software. Oxidative stress markers, including malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity, were measured. Data were analyzed using ANOVA and post-hoc tests ( Results: At 72 hours, the wound closure percentage was significantly higher in the Vitamin C group (80%) compared to the control (50%) and Vitamin E group (70%). The combination group showed the highest healing rate (90%). MDA levels were reduced by 35% in the combination group, while SOD activity increased by 40% compared to the control. The difference between all experimental groups and the control was statistically significant ( Conclusion: Antioxidants, particularly in combination, significantly enhance oral mucosal healing
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Registered trials
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