Evidence map›Paper›PMID 40655591›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Evaluation of Inflammatory Markers and Clinical Outcomes in Patients with Acute Pancreatitis: A Prospective Cohort Study.

Mruga Malay Dhebar, A Likhitha Reddy, Kishore Kumar Natarajan, Ap Aravinda Sathya Seelan, R Manikandan, Aswin Ganesan, Harsh Chandulal Shingala, Sushmitha Rameshbabu, A Prashanth

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Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mruga Malay DhebarDepartment of Cardiology, Wythenshawe Hospital, MFT, Wythenshawe, Manchester, United Kingdom.
A Likhitha ReddyDepartment of General Medicine, Madras Medical College, EVR Periyar Salai, Near G H Hospital, Park Town, Chennai, Tamil Nadu, India.
Kishore Kumar NatarajanDepartment of Academics, Marrow Daily Rounds, Dollars Colony, J P Nagar, Bengaluru, Karnataka, India.
Ap Aravinda Sathya SeelanDepartment of General Surgery, Sri Madhusudan Sai Institute of Medical Sciences and Research, SMSIMSR, Sathya Sai Grama, Muddenahalli, Dist. Chikkaballapur, Karnataka, India.
R ManikandanDepartment of General Medicine, Madras Medical College, EVR Periyar Salai, Near G H Hospital, Park Town, Chennai, Tamil Nadu, India.
Aswin GanesanDepartment of General Medicine, Madras Medical College, EVR Periyar Salai, Near G H Hospital, Park Town, Chennai, Tamil Nadu, India.
Harsh Chandulal ShingalaDepartment of General Medicines, HCG Hospitals, Ayodhya Chowk, HCG Hospital Road, Rajkot, Gujarat, India.
Sushmitha RameshbabuDepartment of General Medicine, Madras Medical College, EVR Periyar Salai, Near G H Hospital, Park Town, Chennai, Tamil Nadu, India.
A PrashanthDepartment of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute pancreatitis (AP) is a sudden inflammatory process of the pancreas that can lead to varying degrees of severity, ranging from mild discomfort to life-threatening conditions. Identifying key inflammatory markers at an early stage is crucial to predicting clinical outcomes and improving management. Objective: This study aims to evaluate the association between inflammatory markers-C-reactive protein (CRP), serum amylase, and white blood cell (WBC) count-and clinical outcomes in patients with acute pancreatitis. Methods: A prospective cohort study involving 120 patients diagnosed with AP was conducted. Inflammatory markers were measured at admission, and their relationship with clinical outcomes, including hospital stay, severity of pancreatitis, and complications, was assessed. Results: Elevated CRP and WBC count were associated with severe pancreatitis and poor outcomes. Serum amylase showed no significant correlation with the severity of the disease. CRP was the strongest predictor of prolonged hospital stay and complications. Conclusion: CRP is a reliable inflammatory marker for predicting severe clinical outcomes in AP, suggesting its use for routine monitoring in clinical practice.

Indexed as

Acute pancreatitisclinical outcomesC-reactive proteininflammatory markerswhite blood cell count

Identifiers

PMID40655591
PMCPMC12244737

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