ArticleJournal of pharmacy & bioallied sciences2025
Evaluating the Efficacy of Bioceramic versus Resin-Based Sealers in Endodontic Treatments: A Comparative Analysis.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Colour change and fracture resistance of endodontically treated teeth after staining and walking bleach: role of filling strategy.Odontology · 2026Article
- Evaluation of the root canal sealing properties and removability of four bioceramic sealers using micro-computed tomographic.BMC oral health · 2026Article
- Use of Bioceramic Sealers in Clinical Practice Among Dentists in Saudi Arabia: A Cross-Sectional Analysis.Cureus · 2026Article
- Oxidative Stress, Pro-Inflammatory Response, Cytotoxicity and Apoptosis Induced by Contemporary Endodontic Sealers in Human Periodontal Ligament Fibroblasts.Journal of functional biomaterials · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Root canal therapy relies heavily on the effectiveness of the sealer used to ensure successful treatment outcomes. Bioceramic and resin-based sealers are commonly employed, each offering distinct advantages and drawbacks. This study aimed to compare the effectiveness of bioceramic versus resin-based sealers in root canal therapy, focusing on microbial leakage, seal integrity, postoperative pain, and healing rates. Methods: A randomized controlled trial was conducted involving 120 patients who required root canal therapy. They were randomly assigned to receive either bioceramic or resin-based sealers. The primary outcomes were microbial leakage and seal integrity, evaluated through clinical and radiographic examinations. Secondary outcomes included postoperative pain and healing rates, monitored over a six-month follow-up period. Results: Bioceramic sealers significantly reduced microbial leakage and enhanced seal integrity compared to resin-based sealers ( Conclusion: Bioceramic sealers demonstrate superior clinical outcomes in terms of microbial leakage prevention and seal integrity, suggesting that they may be more beneficial than resin-based sealers in root canal therapy. These findings support the use of bioceramic materials for improving patient outcomes in endodontic treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.