Evidence map›Paper›PMID 40655360›Full record

ReviewIndian journal of microbiology2025

Characterization and Identification of an Antimicrobial Compound Psilocybin from Psychedelic Mushroom.

Balakrishnan Karthiyayini, Nalliah Nithya Kalyani, Balakrishnan Gowdhami, Manickam Muthuselvam, Dhanasekaran Dharumadurai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Indian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Balakrishnan KarthiyayiniDepartment of Microbiology, Bharathidasan University, Tiruchirappalli, Tamil Nadu India.
Nalliah Nithya KalyaniDepartment of Microbiology, Bharathidasan University, Tiruchirappalli, Tamil Nadu India.
Balakrishnan GowdhamiDepartment of Animal Science, Bharathidasan University, Tiruchirappalli, Tamil Nadu India.
Manickam MuthuselvamDepartment of Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu India.
Dhanasekaran DharumaduraiDepartment of Microbiology, Bharathidasan University, Tiruchirappalli, Tamil Nadu India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antimicrobial compound psilocybin possesses psychoactive properties with therapeutic applications. Psilocybin is the main component naturally present in psychedelic mushrooms and has been utilized in the treatment of depression and neurological disorders. In this study, psychedelic mushrooms were collected from Kodaikanal, Tamil Nadu. They underwent solvent extraction using High Performance Thin Layer Chromatography (HPTLC) and Liquid Chromatography-Mass Spectrometry (LC-MS). Psilocybin, the primary compound, was extracted and evaluated. The extracted psilocybin was then assessed for antimicrobial activity against bacterial and fungal strains using the well diffusion method. Furthermore, HPTLC and LC-MS were employed for the identification of the psilocybin compound. The Rf values of psilocybin were found to be 0.73 and 0.77. Psilocybin inhibited the growth of bacterial and fungal pathogens including Graphical Abstract:

Indexed as

Minimum inhibitory concentrationPsilocybe cubensisPsilocybinPsychedelic mushroom

Identifiers

PMID40655360
PMCPMC12246281

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.