Evidence map›Paper›PMID 40655339›Full record

ReviewIndian journal of microbiology2025

Therapeutic Role of Probiotics in Gut-Brain Axis Under Microgravity.

Moumita Sil, Dyuti Mitra, Nabanita Mukherjee, Maulesh Gadani, Abhijit Chatterjee, Payal Sharma, Arunava Goswami

Abstract readReview
In one paragraph

Review in Indian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Deep space environment empowering drug design and development.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moumita SilBiological Sciences Division, Institute of National Importance, Indian Statistical Institute, 203 B.T. Road, Kolkata, 700108 India.
Dyuti MitraInstitute of National Importance, National Institute of Technology Durgapur, Mahatma Gandhi Road, A Zone, Durgapur, West Bengal 713208 India.
Nabanita MukherjeeBiological Sciences Division, Institute of National Importance, Indian Statistical Institute, 203 B.T. Road, Kolkata, 700108 India.
Maulesh GadaniDepartment of Space, Space Applications Centre, Indian Space Research Organization, Government of India, Ahmedabad, India.
Abhijit ChatterjeeDepartment of Space, Space Applications Centre, Indian Space Research Organization, Government of India, Ahmedabad, India.
Payal SharmaDepartment of Space, Space Applications Centre, Indian Space Research Organization, Government of India, Ahmedabad, India.
Arunava GoswamiBiological Sciences Division, Institute of National Importance, Indian Statistical Institute, 203 B.T. Road, Kolkata, 700108 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microgravity is a state of free fall which one experiences in space. Human-crewed missions are becoming more sophisticated in the ongoing times. The altered gravitational conditions exert several physiological changes in the astronauts. Among many, one of the significantly affected systems and least discussed so far is the neurological system. Earlier studies have shown that exposure to space condition leads to structural changes in the brain, including distorted neurons and apoptotic astrocytes. Recent studies show the velocity of the action potential is reduced. Hippocampal activity is disrupted leading to cognitive impairment. Neuro ocular change occurs in some astronauts. Probiotics like Graphical Abstract:

Indexed as

Bacillus coagulansLactobacillus spMicrogravityNervous systemProbiotics

Identifiers

PMID40655339
PMCPMC12246267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.