ReviewJournal of experimental orthopaedics2025
Clinical outcomes of kinematically aligned medial pivot total knee arthroplasty: A systematic review and meta-analysis of current evidence.
Review in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Clinical and radiographic outcomes of revision total knee arthroplasty with a medial pivot design for aseptic failure.Journal of experimental orthopaedics · 2026Article
- Patient-reported outcomes of kinematically aligned robotic total knee replacement: a single center, single surgeon experience.Journal of robotic surgery · 2026Article
- Medial-pivot total knee arthroplasty demonstrates more constrained mid-flexion gait kinematics than posterior-stabilised total knee arthroplasty under standardised soft-tissue balancing: A randomised controlled trial with a healthy reference cohort.Journal of experimental orthopaedics · 2026Article
- Removing cartilage in the "unworn" side increases the accuracy in restoring the distal joint line in kinematic alignment total knee arthroplasty.Journal of experimental orthopaedics · 2026Article
- Kinematic alignment in total knee replacement successfully restores the native knee phenotype in the short term.Journal of experimental orthopaedics · 2025Article
- Clinical outcomes of kinematically aligned medial pivot total knee arthroplasty: A systematic review and meta-analysis of current evidence.Journal of experimental orthopaedics · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Kinematic alignment (KA) in total knee arthroplasty (TKA) focuses on restoring the natural joint line and ligament balance, potentially improving biomechanics and outcomes over mechanical alignment (MA). The medial pivot (MP) implant enhances joint stability by mimicking physiological knee motion. Still, its role within a KA protocol and the effects of retaining versus sacrificing the posterior cruciate ligament (PCL) are unclear. This study aimed to evaluate the clinical effectiveness, functional outcomes and biomechanical benefits of KA-TKA with MP implants based on the available literature. It also aimed to assess whether PCL retention or sacrifice leads to better postoperative function. Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines. A comprehensive search of PubMed, Embase and Web of Science up to January 2025 identified studies assessing KA-TKA with MP implants. Primary outcomes included patient-reported outcome measures (PROMs), range of motion (ROM), complication rates and implant survivorship. Subgroup analysis compared PCL retention and sacrifice. Results: Fourteen studies (955 patients) met inclusion criteria. KA-TKA with MP implants resulted in significant ROM improvements (+11.35°, increased to +12.50° after sensitivity analysis) and enhanced PROMs (Oxford Knee Score +18.23, increased to +22.27 after sensitivity analysis; Knee Society Score [KSS] +49.61, functional KSS +42.50). No aseptic loosening or implant failures were reported. PCL sacrifice was associated with greater postoperative flexion (125.4° ± 12.1° vs. 116.4° ± 11.8°, Conclusions: KA-TKA with MP implants improves functional recovery, patient satisfaction, and short- to mid-term survivorship, supporting its adoption as a viable alternative to conventional TKA. Further long-term, randomized trials are needed to optimize PCL management and confirm its durability. Level of Evidence: Level IV.
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