Evidence map›Paper›PMID 40655168›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025

Factors Influencing Adherence to Refills and Medications in Patients with Type 2 Diabetes Mellitus in Saudi Arabia: A Questionnaire-Based Study.

Jawad S Alnajjar, Ali A Alwosaibei, Maram A Alameen, Anwar F Alqadeep, Raghad Alanazi, Ali H Alnajim, Abdullah H Al-Ali, Rayan Hamoud Alanazi, Qasem AlJabr

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Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jawad S AlnajjarCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.ORCID 0009-0006-0327-1764
Ali A AlwosaibeiCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Maram A AlameenCollege of Medicine, Taif University, Taif, Saudi Arabia.
Anwar F AlqadeepCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Raghad AlanaziCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Ali H AlnajimCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Abdullah H Al-AliCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Rayan Hamoud AlanaziCollege of Medicine, King Faisal University, Alahsa, Saudi Arabia.
Qasem AlJabrDepartment of Family Medicine, Al-Ahsa Health Cluster, AlAhsa, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes Mellitus is a growing public health concern in Saudi Arabia, with effective management relying on adherence to medications and lifestyle changes. However, non-adherence remains a significant challenge, particularly in regions with varying sociodemographic profiles. Objective: This study aimed to identify factors influencing adherence to medication and refills among patients with Type 2 Diabetes Mellitus in the Al-Ahsa region using the Adherence to Refills and Medications Scale. Methods: A cross-sectional study was conducted from May to July 2024 involving 732 T2DM patients attending governmental primary healthcare centers in Al-Ahsa. A stratified random sampling method was employed to select participants from various geographic strata. Data were collected via structured phone interviews using a validated questionnaire, and clinical data were extracted from medical records. Descriptive statistics, chi-square tests, and multivariable logistic regression were applied to assess factors associated with non-adherence. Results: The overall adherence rate was 52.5%. Significant sociodemographic factors (p < 0.05) associated with adherence included income, marital status, occupation, and area of residence. Clinical factors included age at diabetes onset, diabetic complications, HbA1c level, frequency of glucose monitoring, and comorbidities. Healthcare-related factors such as physician continuity, frequency of visits, and counseling were also significant. Multivariable logistic regression identified major predictors of non-adherence: living in the Southern region (OR = 6.59, p = 0.001), diabetic complications (OR = 1.44, p = 0.047), lack of physician counseling (OR = 2.15, p = 0.005), and poor access to healthcare (OR = 2.34, p = 0.003). Conclusion: Nearly half of T2DM patients in Al-Ahsa were non-adherent to medications and refills. Sociodemographic, clinical, and healthcare system factors significantly influenced adherence. Improving patient education, physician communication, and healthcare access may enhance adherence and outcomes.

Indexed as

chronic disease managementdiabetes managementmedication adherencepatient compliancerefill adherencetype 2 diabetes mellitus

Identifiers

PMID40655168
PMCPMC12255268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.