Evidence map›Paper›PMID 40655106›Full record

ArticleFrontiers in medicine2025

Efficacy and safety analysis of montelukast sodium added on azithromycin in the treatment of

Ying Liang, Wei Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ying LiangDepartment of Pediatric Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wei LiDepartment of Pediatric Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the safety and effectiveness of using montelukast sodium added on azithromycin for the treatment of pediatric Methods: Retrospective analysis showed that 122 children with MPP were divided into a control group (61 cases received azithromycin treatment) and a study group (61 cases received azithromycin combined with montelukast sodium treatment) according to different treatment plans. Both groups were treated for 7 days, and lung function, lung compliance, chest CT signal, inflammatory immune status, and side effects were compared before and after treatment. Result: After a month of treatment, positive end expiratory pressure (PEEP) levels were lower in the research group compared to the control group's kids, whereas forced vital capacity (FVC), tidal volume (TV), peak expiratory flow rate (PEF), pulmonary ventilation per minute (MVV), and pulmonary dynamic compliance (Cdyn) levels were greater ( Conclusion: Azithromycin plus montelukast sodium can effectively improve the lung function and lung compliance of children with MPP, reduce the detection rate of chest CT signs of disease symptoms, and improve the inflammatory and immune state of the body, without increasing adverse reactions, and the clinical application is safe.

Indexed as

azithromycinmontelukast sodiumMycoplasma pneumoniae pneumoniasecuritytherapeutic effect

Identifiers

PMID40655106
PMCPMC12245796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.