SynthesisFrontiers in medicine2025
Prevalence and determinants of anemia in chronic kidney disease patients in Ethiopia: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic kidney disease (CKD) is a progressive and devastating condition affecting over 10% of the global population, with more than 800 million individuals impacted worldwide. Anemia, a critical and debilitating complication of CKD, accelerates disease progression and exacerbates its overall burden. Despite numerous studies exploring the prevalence and determinants of anemia in CKD in Ethiopia, the pooled prevalence remains undefined, highlighting a critical gap in evidence. Objectives: To determine the pooled prevalence of anemia and identify its associated factors among CKD patients in Ethiopia through a systematic review and meta-analysis. Methods: A comprehensive search was carried out for studies with full document and written in English language through an electronic web-based search strategy from databases of PubMed, CINAHL, Cochrane Library, Embase, Google Scholar and Ethiopian University Repository online. The quality of the included studies was assessed using the Joanna Briggs Institute (JBI) checklist. Statistical analyses were performed using STATA version 17. Meta-analysis was conducted with a random-effects model. Heterogeneity among the primary studies was evaluated using Cochran's Q test and the I-squared statistic. To explore potential sources of heterogeneity, subgroup and sensitivity analyses were performed. Results: This systematic review and meta-analysis included seven studies, involving a total of 1,714 CKD patients. The pooled prevalence of anemia among CKD patients was 60.93% (95% CI: 50.05, 71.80), with substantial heterogeneity observed across studies (I Conclusion and recommendations: This systematic review and meta-analysis revealed a high pooled prevalence of anemia among CKD patients, with significant associations with diabetes mellitus comorbidity, and advanced CKD stages. Regional differences were also noted, with Oromia region showing the highest prevalence. We recommend regular anemia screening in CKD patients and the identification and management of risk factors such as diabetes and advanced CKD stages. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024608561, identifier CRD42024608561.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.