Evidence map›Paper›PMID 40655089›Full record

ArticleBasic and clinical neuroscience

Frontotemporal Dementia in Russia: Genetic Structure, Phenotypic Diversity, and Diagnostic Biomarkers.

Yulia A Shpilyukova, Ekaterina Yu Fedotova, Natalia Yu Abramycheva, Alla A Shabalina, Sergey N Illarioshkin

Abstract read
In one paragraph

Article in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yulia A ShpilyukovaResearch Center of Neurology, Moscow, Russia.ORCID https://orcid.org/0000-0001-7214-583X
Ekaterina Yu FedotovaResearch Center of Neurology, Moscow, Russia.ORCID https://orcid.org/0000-0001-8070-7644
Natalia Yu AbramychevaResearch Center of Neurology, Moscow, Russia.ORCID https://orcid.org/0000-0001-9419-1159
Alla A ShabalinaResearch Center of Neurology, Moscow, Russia.ORCID https://orcid.org/0000-0001-9604-7775
Sergey N IllarioshkinResearch Center of Neurology, Moscow, Russia.ORCID https://orcid.org/0000-0002-2704-6282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Frontotemporal dementia (FTD) is a heterogeneous group of diseases with a complex clinical picture, including cognitive decline, behavioral and speech problems, psychiatric symptoms, and parkinsonism. Diagnosis of FTD is complex and requires the use of informative biomarkers. Methods: We examined 226 Russian patients with FTD (mean age 69±10 years) and estimated the prevalence of the three most common genetic causes-mutations in the Results: Mutations in Conclusion: We have conducted the first study of the genetic structure of FTD in Russia, the results of which, combined with other biomarkers, will help improve the diagnosis of the disease.

Indexed as

Amyloid β(Aβ-42)C9orf72Frontotemporal dementia (FTD)GRNMAPTPhosphorylated tau protein (P-tau181)Serum progranulin (PGRN)

Identifiers

PMID40655089
PMCPMC12248181

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.