Evidence map›Paper›PMID 40655075›Full record

ArticleCurrent opinion in biomedical engineering2024

Synthetically programming natural cell-cell communication pathways for tissue engineering.

Leah A Wallach, Connor D Thomas, Pulin Li

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leah A WallachWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Connor D ThomasWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Pulin LiWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Funding

Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ DevelopmentDP2HD108777 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LI, PULIN · 2021 to 2024
$2.9M
NICHD NIH HHS DP2 HD108777
6 · The paper itself

Abstract

Tissue patterning, the process of localizing different cell types to the right place, is critical for tissue function and thus a central goal for tissue engineering. Developing embryos employ diverse cell interaction-based mechanisms to robustly pattern tissues, such as specifying different regions of the central nervous system and aligning all the hair cells in the inner ear. These events range in lengthscale and must all be specified with cell-level precision, imposing challenges for recreating such patterns

Identifiers

PMID40655075
PMCPMC12246774

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.