Evidence map›Paper›PMID 40655062›Full record

ArticleCureus2025

Severe Drug-Induced Dermatosis in a Geriatric Patient: A Case Report.

Stephanie Saldaña Guerrero, Sofia C Lanzarin Quezada, Quitzia L Torres Salazar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephanie Saldaña GuerreroDermatology, Unidad Médica de Alta Especialidad (UMAE) No. 71, Mexican Social Security Institute (IMSS), Torreón, MEX.
Sofia C Lanzarin QuezadaDermatology, General Hospital No. 16, Mexican Social Security Institute (IMSS), Torreón, MEX.
Quitzia L Torres SalazarBiomedical Sciences, Universidad Juárez del Estado de Durango, Durango, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older adults are particularly vulnerable to adverse drug reactions (ADRs) due to age-related physiological changes and polypharmacy. Among these, drug-induced dermatoses are common but often underdiagnosed, especially when presentation is atypical or when patients use unregulated treatments. We report the case of a 71-year-old woman who developed erythroderma, pruritus, and desquamation following the use of prescribed medications alongside topical and herbal self-medication. Hospitalization was required after outpatient treatment failed. Skin biopsy revealed an acute inflammatory pattern consistent with pharmacodermia. Conservative treatment with systemic corticosteroids and topical emollients achieved full remission without complications. This case highlights the diagnostic complexity of ADRs in older adults, particularly in the context of incomplete medication histories and the use of natural products. It emphasizes the need for heightened clinical suspicion, thorough medication review, and pharmacovigilance to prevent escalation of cutaneous toxicity in the elderly.

Indexed as

adverse drug reaction reporting systemsdrug-inducedherbal medicine pharmacovigilancepharmacovigilanceskin diseases

Identifiers

PMID40655062
PMCPMC12255369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.