Evidence map›Paper›PMID 40654919›Full record

ArticlebioRxiv : the preprint server for biology2025

A prophage-encoded sRNA limits lytic phage infection of adherent-invasive

Robert S Brzozowski, Amelia K Schmidt, Nicole L Pershing, Annika Dankwardt, Dominick R Faith, Alex C Joyce, Andrew Maciver, William S Henriques, Shelby E Andersen, Blake Wiedenheft and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Robert S BrzozowskiDivision of Biological Sciences, University of Montana, Missoula, MT, USA.
Amelia K SchmidtDivision of Biological Sciences, University of Montana, Missoula, MT, USA.
Nicole L PershingDepartment of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Annika DankwardtDepartment of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Dominick R FaithDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT, USA.
Alex C JoyceDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT, USA.
Andrew MaciverDivision of Biological Sciences, University of Montana, Missoula, MT, USA.
William S HenriquesDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT, USA.ORCID 0000-0001-9836-3827
Shelby E AndersenDepartment of Immunology and Microbiology, School of Medicine, University of Colorado - Anschutz Medical Campus, School of Medicine, Denver CO, USA.
Blake WiedenheftDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT, USA.
Sherwood R CasjensDepartment of Pathology, University of Utah School of Medicine, Huntsman Cancer Institute, Division of Microbiology and Immunology, Salt Lake City, UT, USA.
Breck A DuerkopDepartment of Immunology and Microbiology, School of Medicine, University of Colorado - Anschutz Medical Campus, School of Medicine, Denver CO, USA.ORCID 0000-0003-4030-9822
June L RoundDepartment of Pathology, University of Utah School of Medicine, Huntsman Cancer Institute, Division of Microbiology and Immunology, Salt Lake City, UT, USA.
Patrick R SecorDepartment of Microbiology & Cell Biology, Montana State University, Bozeman, MT, USA.ORCID 0000-0001-7123-3037

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI MARK T QUINN · 2012 to 2026
$60.0M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
CTSA K12 Program at University of Utah: Early Career Faculty Development ProgramK12TR004413 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MAUREEN A MURTAUGH, Corrine Ione Voils · 2023 to 2026
$3.9M
Bacteriophage pathobiology of inflammatory bowel diseaseR01DK124317 · NIDDK · UNIVERSITY OF UTAH · PI ROUND, JUNE LOUISE · 2020 to 2023
$2.5M
NCATS NIH HHS K12 TR004413NCATS NIH HHS UM1 TR004409NIDDK NIH HHS R01 DK124317NIGMS NIH HHS P20 GM103474
6 · The paper itself

Abstract

Prophages are prevalent features of bacterial genomes that can reduce susceptibility to lytic phage infection, yet the mechanisms involved are often elusive. Here, we identify a small RNA (

Identifiers

PMID40654919
PMCPMC12247714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.