Evidence map›Paper›PMID 40654832›Full record

ArticlebioRxiv : the preprint server for biology2025

Swarm-seq Reveals Functional Divergence in CsrA Homologs Across Bacteria.

Jared T Winkelman, Ethan Yarberry, Jonathan D Winkelman, Sampriti Mukherjee

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jared T WinkelmanDepartment of Molecular Genetics & Cell Biology, University of Chicago, Chicago, IL, USA.
Ethan YarberryDepartment of Molecular Genetics & Cell Biology, University of Chicago, Chicago, IL, USA.
Jonathan D WinkelmanTrestle, LLC, Milwaukee, Wisconsin, USA.
Sampriti MukherjeeDepartment of Molecular Genetics & Cell Biology, University of Chicago, Chicago, IL, USA.ORCID 0000-0002-5509-8776

Funding

Probing the role of sensory cues in the regulation of bacterial biofilm developmentR35GM150803 · NIGMS · UNIVERSITY OF CHICAGO · PI Sampriti Mukherjee · 2023 to 2026
$1.8M
A New Quorum-Sensing Autoinducer Acts with the RhlR Receptor to Control Virulence and Biofilms in Pseudomonas AeruginosaR00GM129424 · NIGMS · UNIVERSITY OF CHICAGO · PI MUKHERJEE, SAMPRITI · 2020 to 2022
$829k
NIGMS NIH HHS R00 GM129424NIGMS NIH HHS R35 GM150803
6 · The paper itself

Abstract

Bacteria employ sophisticated post-transcriptional regulatory mechanisms to adapt to environmental changes. Carbon storage regulator A (CsrA), a highly conserved small RNA-binding protein, serves as a critical post-transcriptional regulator by recognizing GGA motifs in target transcripts and typically repressing translation. Despite extensive research, how this conserved regulator has evolved diverse species-specific regulatory networks remains unclear. Here, using

Identifiers

PMID40654832
PMCPMC12247646

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.